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Genetic and Rare Diseases Information Center (GARD)

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Dubin-Johnson syndrome


Other Names for this Disease

  • Chronic Idiopathic Jaundice
  • Conjugated Hyperbilirubinemia
  • DJS
  • Hyperbilirubinemia 2
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Overview

Dubin-Johnson syndrome is a type of hereditary hyperbilirubinemia with a relatively benign course.[1] Symptoms may include a yellowish color to the skin (jaundice), and a liver that is sometimes enlarged and tender.[2]  The symptoms often do not present until puberty or adulthood. The syndrome interferes with the body's ability to move bilirubin from the liver. In most cases, treatment is not required.[3] 
Last updated: 12/19/2008

References

  1. Habashi SL, Lambiase LR, MK Anand, KJ Mishark, Nguyen C . Dubin-Johnson Syndrome. eMedicine. October 10, 2006; http://emedicine.medscape.com/article/173517-overview. Accessed 12/19/2008.
  2. Dubin Johnson Syndrome. National Organization for Rare Disorders (NORD). 2007; http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=Dubin%20Johnson%20Syndrome. Accessed 12/19/2008.
  3. Dugdale, DC. Dubin-Johnson syndrome. MedlinePlus. July 22, 2008; http://www.nlm.nih.gov/medlineplus/ency/article/000242.htm. Accessed 12/19/2008.
Your Questions Answered
by the Genetic and Rare Diseases Information Center

1 question(s) from the public on Dubin-Johnson syndrome have been answered. See questions and answers. You can also submit a new question.

Basic Information

  • Genetics Home Reference (GHR) contains information on Dubin-Johnson syndrome. This website is maintained by the National Library of Medicine.
  • MedlinePlus was designed by the National Library of Medicine to help you research your health questions, and it provides more information about this topic.
  • The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders. Click on the link to view information on this topic.

In Depth Information

  • Medscape Reference provides information on this topic. Click on the link to view this information. You may need to register to view the medical textbook, but registration is free.
  • Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine. 
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs.  Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Dubin-Johnson syndrome. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • Chronic Idiopathic Jaundice
  • Conjugated Hyperbilirubinemia
  • DJS
  • Hyperbilirubinemia 2
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.