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Dubin-Johnson syndrome

Other Names for this Disease
  • Chronic Idiopathic Jaundice
  • Conjugated Hyperbilirubinemia
  • DJS
  • Hyperbilirubinemia 2
More Names
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Overview


Dubin-Johnson syndrome is a type of hereditary hyperbilirubinemia with a relatively benign course.[1] Symptoms may include a yellowish color to the skin (jaundice), and a liver that is sometimes enlarged and tender.[2]  The symptoms often do not present until puberty or adulthood. The syndrome interferes with the body's ability to move bilirubin from the liver. In most cases, treatment is not required.[3] 

References

  1. Habashi SL, Lambiase LR, MK Anand, KJ Mishark, Nguyen C . Dubin-Johnson Syndrome. eMedicine. http://emedicine.medscape.com/article/173517-overview. Accessed December 19, 2008.
  2. Dubin Johnson Syndrome. National Organization for Rare Disorders (NORD). http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=Dubin%20Johnson%20Syndrome. Accessed December 19, 2008.
  3. Dugdale, DC. Dubin-Johnson syndrome. MedlinePlus. http://www.nlm.nih.gov/medlineplus/ency/article/000242.htm. Accessed December 19, 2008.
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General Information

  • Genetics Home Reference (GHR) contains information on Dubin-Johnson syndrome. Click on the link to go to GHR and review the information.
  • MedlinePlus, a Web site designed by the National Library of Medicine to help you research your health questions, provides more information about this topic. Click on the link to view this information.
  • Medscape Reference provides information on this topic. Click on the link to view this information. You may need to register to view the medical textbook, but registration is free.
  • The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders. Click on the link to view information on this topic.
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs.  Access to this database is free of charge.  Click on the link to read information on this topic.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Dubin-Johnson syndrome. Click on the link to view a sample search on this topic.
  • The The Online Mendelian Inheritance in Man (OMIM) database contains genetics resources that discuss Dubin-Johnson syndrome. Click on the link to go to OMIM and review these resources.