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Ectodermal dysplasia

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Ectodermal dysplasias (ED) are a group of about 150 heritable disorders that affect the ectoderm, a layer of tissue that contributes to the formation of many parts of the body, including the skin, sweat glands, hair, teeth, and nails. Symptoms can range from mild to severe and may include dental abnormalities; brittle, sparse or absent hair; abnormal fingernails; inability to perspire (hypohidrosis); various skin problems; and other symptoms. Different types of ectodermal dysplasias are caused by mutations in different genes, and can be inherited in a variety of ways. There are no cures for ED, but many treatments are available to address the individual symptoms.[1]
Last updated: 4/27/2011


  1. About Ectodermal Dysplasias. National Foundation for Ectodermal Dysplasias. 2010; Accessed 4/21/2011.
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Basic Information

  • Family Village is a global community that integrates information, resources, and communication opportunities on the Internet for persons with cognitive and other disabilities, for their families, and for those who provide services and support. Click on Family Villiage to view a resource page on ectodermal dysplasia.
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