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Epidermolysis bullosa

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Epidermolysis bullosa (EB) is a group of genetic skin diseases that cause the skin to blister very easily. Blisters form in response to minor injuries or friction, such as rubbing or scratching.[1] There are four main types of epidermolysis bullosa:[2]

Identifying the exact type can be hard because there are many subtypes of EB. Within each type or subtype, a person may be mildly or severely affected. The disease can range from being a minor inconvenience to completely disabling, and fatal in some cases.[3] Most types of EB are inherited.[2][4] The inheritance pattern may be autosomal dominant or autosomal recessive.[2] Management involves protecting the skin, reducing friction against the skin, and keeping the skin cool.[3]

Last updated: 10/14/2014


  1. Epidermolysis bullosa simplex. Genetics Home Reference (GHR). 2007; Accessed 4/22/2010.
  2. Berman K. Epidermolysis bullosa. MedlinePlus. 2008; Accessed 4/22/2010.
  3. Epidermolysis bullosa. NORD. June 27, 2013; Accessed 10/14/2014.
  4. Epidermolysis bullosa. 2009; Accessed 4/22/2010.
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2 question(s) from the public on Epidermolysis bullosa have been answered. See questions and answers . You can also submit a new question.

Basic Information

  • DermNet NZ is an online resource about skin diseases developed by the New Zealand Dermatological Society Incorporated. DermNet NZ provides information about this condition.
  • has an information page about epidermolysis bullosa. Click on the link above to access this information.
  • MedlinePlus was designed by the National Library of Medicine to help you research your health questions, and it provides more information about this topic.
  • The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) support research into the causes, treatment, and prevention of arthritis and musculoskeletal and skin diseases, the training of basic and clinical scientists to carry out this research, and the dissemination of information on research progress in these diseases. Click on the link to view information on this topic.
  • The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders. Click on the link to view information on this topic.

General Information

  • eMedicine has 2 articles on this topic from the perspective of !LINK! and !LINK!. You may need to register to view the information online, but registration is free. Click on the links above to view the articles from this medical reference Web site.

In Depth Information

  • Medscape Reference provides information on this topic. Click on the link to view this information. You may need to register to view the medical textbook, but registration is free.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Epidermolysis bullosa. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • EB
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