Epidermolysis bullosa acquisita
Other Names for this Disease
- Acquired epidermolysis bullosa
- EB acquisita
Non-inflammatory or mildly inflammatory EBA affecting only trauma-prone skin (the "classic" form) may cause:
- tense, blood- or pus-filled blisters, mostly on the hands, knees, knuckles, elbows and ankles
- mucous-membrane blisters that rupture easily
- healing with significant scarring and small white spots (milia)
Generalized inflammatory EBA may cause:
- widespread blisters that are not localized to trauma-prone sites
- generalized redness and itching
- healing with minimal scarring
- blisters on various mucous membranes
- significant scarring and dysfunction
The Human Phenotype Ontology provides the following list of signs and symptoms for Epidermolysis bullosa acquisita. If the information is available, the table below includes how often the symptom is seen in people with this condition. You can use the MedlinePlus Medical Dictionary to look up the definitions for these medical terms.
The Human Phenotype Ontology (HPO) has collected information on how often a sign or symptom occurs in a condition. Much of this information comes from Orphanet, a European rare disease database. The frequency of a sign or symptom is usually listed as a rough estimate of the percentage of patients who have that feature.
The frequency may also be listed as a fraction. The first number of the fraction is how many people had the symptom, and the second number is the total number of people who were examined in one study. For example, a frequency of 25/25 means that in a study of 25 people all patients were found to have that symptom. Because these frequencies are based on a specific study, the fractions may be different if another group of patients are examined.
Sometimes, no information on frequency is available. In these cases, the sign or symptom may be rare or common.
- Epidermolysis bullosa acquisita. DermNet NZ. December 29, 2013; http://www.dermnetnz.org/immune/epidermolysis-bullosa-acquisita.html. Accessed 2/27/2014.
- Gupta R, Woodley DT, Chen M. Epidermolysis bullosa acquisita. Clin Dermatol. January-February, 2012; 30(1):60-69. Accessed 3/3/2014.