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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Familial idiopathic basal ganglia calcification


Other Names for this Disease
  • Bilateral striopallidodentate calcinosis
  • BSPDC
  • Cerebral calcification nonarteriosclerotic idiopathic adult-onset
  • Fahr disease, familial (formerly)
  • Ferrocalcinosis, cerebrovascular
More Names
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Cause


Newline Maker

What causes familial idiopathic basal ganglia calcification [FIBGC]?

FIBGC is a genetic condition; mutations in the SLC20A2 gene are thought to cause about half of the cases of FIBGC. Mutations in the PDGFRB gene have also been shown to cause FIBGC. In the remaining cases, the genes responsible have not yet been found. However, there is a strong association to changes in chromosomes 2, 7, 9 and 14 and FIBGC.[1]
Last updated: 8/2/2013

References
  1. Familial idiopathic basal ganglia calcification. Genetics Home Reference (GHR). February 2013; http://ghr.nlm.nih.gov/condition/familial-idiopathic-basal-ganglia-calcification. Accessed 10/18/2013.