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Familial adenomatous polyposis
Other Names for this Disease
- Adenomatous polyposis coli
- Adenomatous polyposis of the colon
- Familial adenomatous polyposis of the colon
- Familial intestinal polyposis
- Familial multiple polyposis
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Familial adenomatous polyposis (FAP) is an inherited colorectal cancer syndrome. Cancer usually develops in the lower part of the digestive system, including the large intestine (colon) and rectum. People with the classic type of familial adenomatous polyposis may begin to develop multiple noncancerous (benign) polyps (growths) in the colon as early as their teenage years. The average age at which an individual develops colon cancer in classic familial adenomatous polyposis is about 39 years. Mutations in the APC gene cause classic familial adenomatous polyposis.
- Familial adenomatous polyposis. Genetics Home Reference Web site. http://ghr.nlm.nih.gov/condition=familialadenomatouspolyposis. Accessed April 6, 2010.
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- The The Online Mendelian Inheritance in Man (OMIM) database contains genetics resources that discuss Familial adenomatous polyposis. Click on the link to go to OMIM and review these resources.