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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Nonalcoholic steatohepatitis

*

* Not a rare disease

Other Names for this Disease

  • NASH
  • Non-alcoholic fatty liver disease
  • Non-alcoholic steatohepatitis
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Overview

Nonalcoholic steatohepatitis, or NASH, is a common, often “silent” liver disease. It resembles alcoholic liver disease, but occurs in people who drink little or no alcohol. The major feature in NASH is fat in the liver, along with inflammation and damage. Most people with NASH feel well and are not aware that they have a liver problem. Nevertheless, NASH can be severe and can lead to cirrhosis, in which the liver is permanently damaged and scarred and no longer able to work properly. NASH most often occurs in people who are middle aged and overweight or obese. Affected individuals may also have elevated levels of blood lipids (such as cholesterol and triglycerides) and many have diabetes or prediabetes. Treatment is centered around working towards a healthy lifestyle, including weight reduction, dietary modification, increased activity and avoidance of alcohol and unnecessary medications. The underlying cause of NASH remains unclear.[1]
Last updated: 2/24/2012

References

  1. Nonalcoholic Steatohepatitis. National Digestive Diseases Information Clearinghouse (NDDIC). 2006; http://digestive.niddk.nih.gov/ddiseases/pubs/nash/.
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Please contact us with your questions about Nonalcoholic steatohepatitis. We will answer your question and update these pages with new resources and information.

Basic Information

  • The National Digestive Diseases Information Clearinghouse (NDDIC), part of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), offers information on this condition. Click on the link to view information on this topic.
  • MayoClinic.com provides information about nonalcoholic fatty liver disease, including nonalcoholic steatohepatitis. Click on the link to view this information. 

In Depth Information

  • Medscape Reference provides information on this topic. Click on the link to view this information. You may need to register to view the medical textbook, but registration is free.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Nonalcoholic steatohepatitis. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • NASH
  • Non-alcoholic fatty liver disease
  • Non-alcoholic steatohepatitis
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.