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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Fibrodysplasia ossificans progressiva


Other Names for this Disease

  • FOP
  • Myositis ossificans
  • Myositis ossificans progressiva
  • Progressive myositis ossificans
  • Progressive ossifying myositis
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Treatment

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How might fibrodysplasia ossificans progressiva be treated?

There is currently no definitive treatment.  However, a brief course of high-dose corticosteroids, such as Prednisone, started within the first 24 hours of a flare-up, may help reduce the intense inflammation and tissue swelling seen in the early stages of fibrodysplasia ossificans progressiva.  Other medications, such as muscle relaxants, mast cell inhibitors, and aminobisphosphonates, if appropriate, should be closely monitored by a physician.  Surgery to remove heterotopic and extra-skeletal bone is risky and can potentially cause painful new bone growth. [1]
Last updated: 3/21/2011

References
  1. Pignolo R, Kaplan F. Pediatric Fibrodysplasia Ossificans Progressiva. E-medicine. July 30, 2009; http://emedicine.medscape.com/article/1007104-overview. Accessed 3/17/2011.


Management Guidelines

Clinical Trials & Research for this Disease

  • The Research Portfolio Online Reporting Tool (RePORT) provides access to reports, data, and analyses of research activities at the National Institutes of Health (NIH), including information on NIH expenditures and the results of NIH-supported research. Although these projects may not conduct studies on humans, you may want to contact the investigators to learn more. To search for studies, enter the disease name in the "Text Search" box. Then click "Submit Query".
Other Names for this Disease
  • FOP
  • Myositis ossificans
  • Myositis ossificans progressiva
  • Progressive myositis ossificans
  • Progressive ossifying myositis
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.