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Genetic and Rare Diseases Information Center (GARD)

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Gardner-Diamond syndrome

Other Names for this Disease
  • Autoerythrocyte sensitization
  • Autoerythrocyte sensitization purpura
  • Painful bruising syndrome
  • Psychogenic purpura
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Gardner-Diamond syndrome is a condition characterized by episodes of unexplained, painful bruising, mostly occurring on the arms, legs, trunk and/or face.[1][2] The disorder is most common in Caucasian women who have mental illness or emotional stress. Symptoms typically include the formation of multiple, small, purple bruises that may be associated with redness and swelling. Most affected individuals report that the bruising occurs either spontaneously or some time after trauma or surgery. The cause of the condition is poorly understood. Management typically involves psychiatric treatment.[1]
Last updated: 9/12/2011


  1. Benjamin P Geisler, Bruce J Dezube. Psychogenic purpura (Gardner-Diamond syndrome). UpToDate. January 19, 2011; Accessed 9/12/2011.
  2. OL Ivanov, AN Lvov, AV Michenko, J Künzel, P Mayser, U Gieler. Autoerythrocyte sensitization syndrome (Gardner–Diamond syndrome): review of the literature. Journal of the European Academy of Dermatology and Venereology. 2009; 23(5):499-504.
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