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Pemphigoid gestationis
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Overview
Pemphigoid gestationis (PG), also known as gestational pemphigoid or herpes gestationis, is an autoimmune skin disorder associated with pregnancy. Signs and symptoms of the disorder typically present during the second or third trimester of pregnancy, but it may occur at any time during pregnancy or anywhere up to six weeks after giving birth. Although the signs and symptoms are variable, a red, itchy rash with blisters is common. The rash may occur in different parts of the body, but usually develops near the belly button and/or the arms and legs. The condition is caused by the production of antibodies that attack the person's body, leading to damage and consequently blister formation. Treatment generally involves systemic corticosteroids.[1]
References
- Flangini Cobo M, Giuli Santi C, Wakisaka Maruta C, Aoki V. Pemphigoid Gestationis: Clinical and Laboratory Evaluation. Clinics. 2009.
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General Information
- DermNet NZ is an online resource about skin diseases developed by the New Zealand Dermatological Society Incorporated. DermNet NZ provides information about this condition. Click on the link to view the information.
- Medscape Reference provides information on this topic. Click on the link to view this information. You may need to register to view the medical textbook, but registration is free.
- The Merck Manuals Online Medical Library provides information on this condition. Click on the link to view the information.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Pemphigoid gestationis. Click on the link to view a sample search on this topic.