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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Glucose-galactose malabsorption


Other Names for this Disease

  • Carbohydrate intolerance of glucose galactose
  • Complex carbohydrate intolerance
  • GGM
  • Glucose galactose malabsorption deficiency
  • Monosaccharide malabsorption
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Overview

Glucose-galactose malabsorption is an inherited condition in which the cells lining the intestine cannot take in the sugars glucose and galactose, which prevents proper digestion. This condition typically becomes apparent in the first few weeks of a baby's life. When fed breast milk or regular infant formulas, affected infants experience severe diarrhea resulting in life-threatening dehydration, acidosis, and weight loss. Some children are better able to tolerate glucose and galactose as they get older. Affected individuals can also develop kidney stones or more widespread deposits of calcium within the kidneys. This condition is caused by mutations in the SLC5A1 gene and is inherited in an autosomal recessive fashion.[1]
Last updated: 8/31/2011

References

  1. Glucose-galactose malabsorption. Genetics Home Reference. July 2007; http://ghr.nlm.nih.gov/condition/glucose-galactose-malabsorption. Accessed 8/31/2011.
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Please contact us with your questions about Glucose-galactose malabsorption. We will answer your question and update these pages with new resources and information.

Basic Information

  • Genetics Home Reference (GHR) contains information on Glucose-galactose malabsorption. This website is maintained by the National Library of Medicine.
  • The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders. Click on the link to view information on this topic.

In Depth Information

  • The Online Mendelian Inheritance in Man (OMIM) is an catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine. 
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs.  Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Glucose-galactose malabsorption. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • Carbohydrate intolerance of glucose galactose
  • Complex carbohydrate intolerance
  • GGM
  • Glucose galactose malabsorption deficiency
  • Monosaccharide malabsorption
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.