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Genetic and Rare Diseases Information Center (GARD)

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Hemangioendothelioma


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Overview

The term hemangioendothelioma describes several types of vascular neosplasms and includes both non-cancerous (benign) and cancerous (malignant) growths. The term has also been applied to those that show "borderline" behavior, intermediate between entirely benign hemangiomas and highly malignant angiosarcomas.[1] Hemangioendotheliomas are caused by abnormal growth of blood vessel cells, although the exact underlying cause for the abnormal growth is unknown. They can also develop in an organ, such as the liver or lung. They usually grow slowly and can sometimes spread to other tissues in the body (metastasize).[2][1] Examples of types of hemangioendotheliomas include spindle cell hemangioma; papillary intralymphatic (Dabska tumor); retiform; kaposiform; epithelioid; pseudomyogenic (epithelioid sarcoma-like hemangioendothelioma); and composite.[1] Treatment depends on the type of hemangioendothelioma present but typically includes surgical excision (removal).
Last updated: 7/10/2013

References

  1. Requena L, Kutzner H. Hemangioendothelioma. Semin. Diagn. Pathol. February 2013; 30(1):29-44.
  2. Sarcoma - Adult Soft Tissue Cancer. American Cancer Society. July 6, 2010; http://www.cancer.org/Cancer/Sarcoma-AdultSoftTissueCancer/DetailedGuide/sarcoma-adult-soft-tissue-cancer-soft-tissue-sarcoma. Accessed 2/14/2011.
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Basic Information

  • The American Cancer Society provides information on hemangioendothelioma in a fact sheet on soft-tissue sarcomas.
  • The National Cancer Institute provides the most current information on cancer for patients, health professionals, and the general public.  Click on the link to view information on this topic. 

In Depth Information

  • PubMed is a searchable database of medical literature and lists journal articles that discuss Hemangioendothelioma. Click on the link to view a sample search on this topic.
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.