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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Hailey-Hailey disease


Other Names for this Disease

  • BCPM
  • Benign chronic pemphigus
  • Benign familial pemphigus
  • Familial benign pemphigus
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Treatment

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How might Hailey-Hailey disease be treated?

There is no specific treatment for Hailey-Hailey disease and management generally focuses on the specific symptoms and severity in each person. Affected people are encouraged to avoid "triggers" such as sunburn, sweating, and friction, and to keep the affected areas dry. Sunscreen, loose clothing, moisturizing creams, and avoiding excessive heat may help prevent outbreaks.[1] Trying to prevent bacterial, viral, and fungal infections in the affected areas is also important, and drugs used to treat or prevent these infections are commonly used.[1][2]

Topical medications (such as mild corticosteroid creams and topical antibiotics) may improve symptoms in milder forms.[1][2] Cool compresses and dressings may also help.[1] More severe cases may require systemic antibiotics and/or stronger corticosteroid creams.[1] Carbon dioxide laser treatment may be effective for severe forms. In very severe cases, surgery can be performed to remove the affected skin, but skin grafts are usually necessary to repair the wounds.[3]
Last updated: 5/14/2014

References
  1. Hailey-Hailey disease. NORD. August 2, 2012; http://www.rarediseases.org/rare-disease-information/rare-diseases/byID/1223/viewAbstract. Accessed 5/14/2014.
  2. Familial benign chronic pemphigus. Orphanet. June, 2006; http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=2841. Accessed 5/14/2014.
  3. Hailey-Hailey disease. DermNet NZ. December 29, 2013; http://www.dermnetnz.org/systemic/familial-pemphigus.html. Accessed 5/14/2014.


Clinical Trials & Research for this Disease

  • ClinicalTrials.gov lists trials that are studying or have studied Hailey-Hailey disease. Click on the link to go to ClinicalTrials.gov to read descriptions of these studies.
Other Names for this Disease
  • BCPM
  • Benign chronic pemphigus
  • Benign familial pemphigus
  • Familial benign pemphigus
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.