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Genetic and Rare Diseases Information Center (GARD)

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Hailey-Hailey disease


Other Names for this Disease

  • BCPM
  • Benign chronic pemphigus
  • Benign familial pemphigus
  • Familial benign pemphigus
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Overview

Hailey-Hailey disease is a hereditary blistering skin disease. Signs and symptoms include a painful rash and blistering in skin folds such as the armpits, groin, neck, under the breasts, and between the buttocks. Secondary bacterial infections are not uncommon. Symptoms are often worse in summer months due to heat, sweating and friction.[1] Hailey-Hailey disease is caused by mutations in the ATP2C1 gene and is inherited in an autosomal dominant manner.[2] Treatment focuses on reducing symptoms and preventing flares.[1]
Last updated: 5/14/2014

References

  1. Hailey-Hailey disease. DermNet NZ. December 29, 2013; http://www.dermnetnz.org/systemic/familial-pemphigus.html. Accessed 5/14/2014.
  2. Benign chronic pemphigus. Genetics Home Reference. May, 2013; http://ghr.nlm.nih.gov/condition/benign-chronic-pemphigus. Accessed 5/14/2014.
Your Questions Answered
by the Genetic and Rare Diseases Information Center

2 question(s) from the public on Hailey-Hailey disease have been answered. See questions and answers. You can also submit a new question.

Basic Information

  • DermNet NZ is an online resource about skin diseases developed by the New Zealand Dermatological Society Incorporated. DermNet NZ provides information about this condition.
  • Genetics Home Reference contains information on Hailey-Hailey disease. This website is maintained by the National Library of Medicine.
  • The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders. Click on the link to view information on this topic.

In Depth Information

  • Medscape Reference provides information on this topic. Click on the link to view this information. You may need to register to view the medical textbook, but registration is free.
  • The Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine. 
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs.  Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Hailey-Hailey disease. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • BCPM
  • Benign chronic pemphigus
  • Benign familial pemphigus
  • Familial benign pemphigus
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.