Hereditary fructose intolerance
Other Names for this Disease
- ALDOB deficiency
- Aldolase B deficiency
- Fructose intolerance, hereditary
- Fructose-1,6-bisphosphate aldolase B deficiency
- Fructose-1-phosphate aldolase deficiency
Your QuestionMy grandson has been diagnosed with hereditary fructose intolerance. The family has not been able to see a dietician, and they are having a hard time finding good recipes. Please give me some info so I can help them.
We have identified the following information that we hope you find helpful. If you still have questions, please contact us.
Questions on this page
- What is hereditary fructose intolerance (HFI)?
- What are the symptoms of hereditary fructose intolerance (HFI)?
- What causes hereditary fructose intolerance (HFI)?
- How is hereditary fructose intolerance (HFI) inherited?
- How is hereditary fructose intolerance (HFI) treated?
- What specialists can help diagnose and treat hereditary fructose intolerance (HFI)?
The symptoms of HFI include:
- Poor feeding as a baby
- Increased or prolonged neonatal jaundice
- Excessive sleepiness
- Intolerance for fruits
- Avoidance of fruits and fructose/sucrose-containing foods
- Doing well after eating foods without fructose/sucrose
The early symptoms of fructose intolerance may resemble those of galactosemia: irritability, jaundice, vomiting, convulsions and an enlarged liver and spleen. Later problems relate more to liver disease.
Additional information on foods to avoid if you have HFI is available from the Mayo clinic.
American Dietetic Association
120 South Riverside Plaza, Suite 2000
Chicago, Illinois 60606-6995
Consumer nutrition information and referrals
Public Web site: http://www.eatright.org/Public/
Since HFI is a genetic condition, we suggest that you contact a genetics clinic to discuss this information with a genetics professional. To find a genetics clinic near you, we recommend contacting your primary doctor for a referral. The following online resources can also help you find a genetics professional in your community:
* GeneClinics - A searchable directory of US and international genetics and prenatal diagnosis clinics. To locate genetics clinics in the United States, go to the following link and click on 'Clinic Directory' to find a genetic service close to you. To locate genetics clinics outside of the United States, go the following link, click on 'Clinic Directory', and click on 'International Clinic Directory Search'.
* ResourceLink - A database of genetics counseling services, searchable by location, name, institution, type of practice, or specialty. Hosted by the National Society of Genetic Counselors.
The American Society of Human Genetics (ASHG) is a professional organization of research and clinical geneticists. The ASHG maintains a database of these geneticists, some of which live outside of the United States. If you are interested in obtaining a list of the geneticists in your country, some of which may only be researchers and may not offer medical care, please visit the following hyperlink, enter 'YOUR COUNTRY'S NAME' in the 'Country' search box, and click on 'Click to Begin Search'.
- Kirmse B. Hereditary fructose intolerance. Medline Plus Web site. May 2, 2007; http://www.nlm.nih.gov/medlineplus/ency/article/000359.htm. Accessed 3/17/2009.
- Fructose intolerance, hereditary. OMIM Database. October 30, 2006; http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=229600. Accessed 2/17/2009.