Hereditary sensory neuropathy type 1
Other Names for this Disease
- Hereditary sensory and autonomic neuropathy type 1
- HSAN 1
- Neuropathy hereditary sensory and autonomic type 1
- Neuropathy hereditary sensory radicular, autosomal dominant
sensorineural hearing loss. Symptoms of HSN1 typically begin during a person's teens or twenties and worsen over time. The condition may be caused by any of several genes, depending on the form of HSN1 a person has. For example, HSN type 1A is caused by mutations in the SPTLC1 gene. All forms of HSN1 are inherited in an autosomal dominant manner. If symptoms are treated properly, the condition does not appear to affect life expectancy.Hereditary sensory neuropathy type 1 (HSN1) is a neurological condition characterized by nerve abnormalities in the legs and feet. Many people with this condition have tingling, weakness, and a reduced ability to feel pain and sense hot and cold. Some affected people do not lose sensation, but instead feel shooting pains in their legs and feet. As HSN1 progresses, sensory problems can affect the hands, arms, shoulders, and abdomen. In rare cases, people with this condition develop
Last updated: 9/2/2014
- Hereditary sensory neuropathy type 1. Genetics Home Reference (GHR). December 2009; http://ghr.nlm.nih.gov/condition/hereditary-sensory-neuropathy-type-1. Accessed 6/2/2014.
- HEREDITARY SENSORY NEUROPATHY TYPE I. NORD. July 11, 2014; http://www.rarediseases.org/rare-disease-information/rare-diseases/byID/799/viewAbstract. Accessed 9/2/2014.
- Genetics Home Reference (GHR) contains information on Hereditary sensory neuropathy type 1. This website is maintained by the National Library of Medicine.
- The National Institute of Neurological Disorders and Stroke (NINDS) (NINDS) collects and disseminates research information related to neurological disorders. Click on the link to view information on this topic.
- The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders. Click on the link to view information on this topic.
- Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine.
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