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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Hidradenitis suppurativa

*

* Not a rare disease

Other Names for this Disease

  • Acne inversa
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Symptoms

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What are the signs and symptoms of hidradenitis suppurativa?

Hidradenitis is the medical term for inflammation of hair follicles, oil (sebaceous) ducts, and sweat glands in the skin. The term suppurativa means that the infection causes pus to form. Those with HS develop hidradenitis due to obstruction of hair follicles, which causes secondary infection and inflammation of the apocrine glands. The lesions most commonly develop in the groin and axillae (under arms). The typical lesion is a painful inflammatory papule (small, solid, raised skin lesion), nodule, or abscess (pus-filled inflamed tissue). Affected individuals may experience pain, scarring, recurrent discharge, and smell from the lesions. It is thought that hidradenitis can be aggravated by stress, heat, sweating, or friction. Persistent lesions may lead to the formation of sinus tracts, or tunnels connecting the abscesses under the skin. At this stage, progression of the disease, bacterial infection, and cellulites (deep tissue inflammation) in the area are also likely.[1]
Last updated: 6/7/2011

The Human Phenotype Ontology provides the following list of signs and symptoms for Hidradenitis suppurativa. If the information is available, the table below includes how often the symptom is seen in people with this condition. You can use the MedlinePlus Medical Dictionary to look up the definitions for these medical terms.

Signs and Symptoms Approximate number of patients (when available)
Recurrent cutaneous abscess formation 90%
Abnormality of temperature regulation 50%
Acne 50%
Atypical scarring of skin 50%
Pruritus 50%
Arthritis 7.5%
Hyperhidrosis 7.5%
Intestinal fistula 7.5%
Lymphedema 7.5%
Microcytic anemia 7.5%
Neoplasm of the skin 7.5%
Weight loss 7.5%
Atypical scarring of skin -
Autosomal dominant inheritance -

Last updated: 11/3/2014

The Human Phenotype Ontology (HPO) has collected information on how often a sign or symptom occurs in a condition. Much of this information comes from Orphanet, a European rare disease database. The frequency of a sign or symptom is usually listed as a rough estimate of the percentage of patients who have that feature.

The frequency may also be listed as a fraction. The first number of the fraction is how many people had the symptom, and the second number is the total number of people who were examined in one study. For example, a frequency of 25/25 means that in a study of 25 people all patients were found to have that symptom. Because these frequencies are based on a specific study, the fractions may be different if another group of patients are examined.

Sometimes, no information on frequency is available. In these cases, the sign or symptom may be rare or common.


References
  1. Pokala N & Geibe J. Surgery for Hidradenitis Suppurativa . eMedicine Journal. April 2008; http://emedicine.medscape.com/article/190972-overview#showall. Accessed 6/7/2011.


Other Names for this Disease
  • Acne inversa
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.