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Genetic and Rare Diseases Information Center (GARD)

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Hirschsprung's disease


Other Names for this Disease

  • Aganglionic megacolon
  • Hirschsprung disease 1
  • Hirschsprung disease type 1
  • HSCR
  • HSCR 1
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Overview

Hirschsprung disease is a disease of the large intestine or colon. People with this disease do not have the nerve cells in the intestine required to expel stools from the body normally. Symptoms of Hirschsprung disease usually show up in very young children, but sometimes not until adolescence or adulthood. The symptoms may vary with age, but often involve constipation and/or obstruction of the bowel.[1]
Last updated: 10/17/2013

References

  1. Hirschsprung disease. Genetics Home Reference (GHR). August 2012; http://ghr.nlm.nih.gov/condition/hirschsprung-disease. Accessed 10/17/2013.
Your Questions Answered
by the Genetic and Rare Diseases Information Center

3 question(s) from the public on Hirschsprung's disease have been answered. See questions and answers. You can also submit a new question.

Basic Information

  • Genetics Home Reference (GHR) contains information on Hirschsprung's disease. This website is maintained by the National Library of Medicine.
  • MedlinePlus was designed by the National Library of Medicine to help you research your health questions, and it provides more information about this topic.
  • The Merck Manual Online Medical Library provides information on digestive tract defects. Click on Merck Manual to view the information page.
  • The National Digestive Diseases Information Clearinghouse (NDDIC), part of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), offers information on this condition. Click on the link to view information on this topic.
  • The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders. Click on the link to view information on this topic.

In Depth Information

  • Medscape Reference provides information on this topic. Click on the link to view this information. You may need to register to view the medical textbook, but registration is free.
  • MeSH® (Medical Subject Headings) is a terminology tool used by the National Library of Medicine. Click on the link to view information on this topic.
  • The Online Mendelian Inheritance in Man (OMIM) is an catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine. 
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs.  Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Hirschsprung's disease. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • Aganglionic megacolon
  • Hirschsprung disease 1
  • Hirschsprung disease type 1
  • HSCR
  • HSCR 1
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.