Hyperprolinemia type 2
Other Names for this Disease
- 1 alpha pyrroline-5-carboxylate dehydrogenase deficiency
- Delta1-pyrroline-5-carboxylate dehydrogenase deficiency
- Hyperprolinemia type 2
- Type 2 hyperprolinemia
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mental retardation and seizures; however, the symptoms of this disorder vary in severity among affected individuals.Hyperprolinemia type 2 results in an excess of a particular protein building block (amino acid), called proline, in the blood. This condition generally occurs when proline is not broken down properly by the body. Hyperprolinemia type 2 causes proline levels in the blood to be 10 to 15 times higher than normal, and it also causes high levels of a related compound called pyrroline-5-carboxylate. Some people with this condition develop mild
Last updated: 11/1/2013
- Hyperprolinemia. Genetics Home Reference Website . June 2007; http://ghr.nlm.nih.gov/condition=hyperprolinemia. Accessed 11/3/2008.
- Genetics Home Reference (GHR) contains information on Hyperprolinemia type 2. This website is maintained by the National Library of Medicine.
- The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders. Click on the link to view information on this topic.
- Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine.
- Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Hyperprolinemia type 2. Click on the link to view a sample search on this topic.