Other Names for this Disease
- Aglossia - adactylia
- Aglossia adactylia
- Hypoglossia - hypodactyly
- Hypoglossia-hypodactylia syndrome
- Jussieu syndrome
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Your QuestionMy husband and I are adopting a 7 year old boy who has been diagnosed with Hanhart syndrome. We need help. Is there anybody who could give us information and guidance about this condition?
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Hanhart syndrome is a rare birth defect in which the main signs are a short, incompletely developed tongue (hypoglossia); absent or partially missing fingers and/or toes (hypodactylia); malformed arms and/or legs (peromelia); and an extremely small jaw (micrognathia).The severity of these physical abnormalities varies greatly among individuals, and children with this disorder often have some, but not all, of the symptoms. The cause of Hanhart syndrome is not fully understood. It appears to occur sporadically, being unlikely to recur in a family. Treatment may involve orthopedic and/or plastic surgery for limb abnormalities.
Last updated: 3/23/2011
The main features of Hanhart syndrome include a short, incompletely developed tongue (hypoglossia); absent or partially missing fingers and/or toes (hypodactylia); malformed arms and/or legs (peromelia); and an extremely small jaw (micrognathia). Retrognathia (receding jaw) is also a common feature of Hanhart syndrome. Other features that have been reported include hypodontia (missing teeth) and the absence of major salivary glands. The limb abnormalities in individuals with Hanhart syndrome have ranged from shortened fingers or toes and oligodactyly (missing fingers or toes) to more severe abnormalities such as absent or malformed limbs. In an affected individual, any limb may be affected. The severity of the physical abnormalities associated with Hanhart syndrome varies greatly among affected individuals, and children with this disorder often have some, but not all, of the symptoms.
Last updated: 3/23/2011
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Last updated: 9/29/2014
- Hanhart syndrome. NORD. 2004; http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=Hanhart%20Syndrome. Accessed 3/22/2011.
- Raoul Hennekam, Judith Allanson, Ian Krantz. Gorlin's Syndromes of the Head and Neck. USA: Oxford University Press; February 5, 2010;
- E. Robert-Gnansia. Hypoglossia - hypodactyly. Orphanet. July 2005; http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=989. Accessed 3/22/2011.