Other Names for this Disease
- Dextrocardia bronchiectasis and sinusitis
- Siewert syndrome
Your QuestionI have Kartagener syndrome. As I get older, it seems as if my symptoms are getting worse. I am on a long-term regimen of antibiotics and wondered if there were other options for management of this condition or resources where I can obtain support for a healthy lifestyle.
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Questions on this page
- What is Kartagener syndrome?
- What are the signs and symptoms of Kartagener syndrome?
- How might Kartagener syndrome be treated?
- Where can I learn more about current research for Kartagener syndrome, including studies which may be looking at this condition in different age groups and those working towards new and better ways to treat the symptoms?
- What is the prognosis for individuals with Kartagener syndrome?
- Where can I find support for individuals with Kartagener syndrome?
Individuals also have situs inversus totalis, a mirror-image reversal of all organs. The reversed organs do not usually pose a problem. Males with Kartagener syndrome may be infertile secondary to impaired sperm motility because the flagella of the sperm and cilia often (but not always) have the same defects. Some women with Kartagener syndrome have normal fertility, but others have impaired fertility and an increased risk for ectopic pregnancy because of impaired ciliary function in the fallopian tubes.
Where can I learn more about current research for Kartagener syndrome, including studies which may be looking at this condition in different age groups and those working towards new and better ways to treat the symptoms?
The Genetic Disorders Of Mucociliary Clearance Consortium is a network of four U.S. centers (University of North Carolina at Chapel Hill, Washington University in St. Louis, University of Washington, and University of Colorado) that are collaborating in the diagnostic testing, genetic studies, and clinical trials in patients with impairments in mucociliary clearance, focusing on primary ciliary dyskinesia, cystic fibrosis, and pseudohypoaldosteronism. Ultimately, this group hopes to better define the clinical pathogenesis of these important airway diseases, improve or expand diagnostic testing, and develop new and effective treatments. To read more about this consortium and their involvement with primary ciliary dyskinesia and Kartagener syndrome, click on the above link.
The PCD Foundation is dedicated to increasing awareness of inherited ciliary disorders and to providing education and advocacy for affected individuals and their caregivers.
PCD (Primary Ciliary Dyskinesia) Foundation
29252 N. 22nd. Lane
Phoenix AZ 85085
Phone: 623-215-2032 or 612-396-1179
- Zariwala MA, Knowles MR, Leigh MW. Primary Ciliary Dyskinesia. GeneReviews. October 6, 2009; http://www.ncbi.nlm.nih.gov/books/NBK1122/. Accessed 7/12/2011.
- Casanova MS, Tuji FM, Yoo HJ, Haiter-Neto F. Kartagener syndrome. Dentomaxillofac Radiol. September 2006; http://www.ncbi.nlm.nih.gov/pubmed/16940490. Accessed 7/12/2011.
- Primary ciliary dyskinesia. Genetics Home Reference (GHR). August 2010; http://ghr.nlm.nih.gov/condition/primary-ciliary-dyskinesia. Accessed 7/12/2011.
- Primary Ciliary Dyskinesia. American Lung Association. 2011; http://www.lungusa.org/lung-disease/primary-ciliary-dyskinesia/. Accessed 7/12/2011.
- Bent JP, Mosenifar Z. Kartagener Syndrome. eMedicine. April 2009; http://emedicine.medscape.com/article/299299-overview. Accessed 7/12/2011.
- Kartagener Syndrome. Online Mendelian Inheritance in Man (OMIM). June 2011; http://omim.org/entry/244400. Accessed 7/12/2011.