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Other Names for this Disease
- Dextrocardia bronchiectasis and sinusitis
- Siewert syndrome
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Kartagener syndrome is caused by an inherited defective gene which causes the cilia to be either immotile (unable to move) or dysmotile (they move incorrectly). As a result, mucous cannot be cleared from the lungs, paranasal sinuses and ears. Bacteria and other irritants in the mucous lead to frequent respiratory infections. Kartagener syndrome is inherited in an autosomal recessive manner. Recent studies have shown that Kartagener syndrome is linked to a region on chromosome 15q.
Last updated: 8/22/2011
- Zariwala M. Primary Ciliary Dyskinesia. National Organization for Rare Disorders (NORD). 2008; http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=Primary%20Ciliary%20Dyskinesia. Accessed 10/13/2008.
- Geremek M, Schoenmaker F, Zietkiewicz E, Pogorzelski A, Diehl S, Wijmenga C, Witt M. Eur J Hum Genet. June 2008; http://www.ncbi.nlm.nih.gov/pubmed/18270537. Accessed 10/13/2008.