Your browser does not support javascript:   Search for gard hereSearch for news-and-events here.


Genetic and Rare Diseases Information Center (GARD)

Print friendly version

Kikuchi disease

Other Names for this Disease
  • Histiocytic necrotising lymphadenitis
  • Kikuchi necrotizing lymphadenitis
  • Kikuchi's disease
  • Kikuchi-Fujimoto's disease
  • Nosocomial Kikuchi's disease
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.


Newline Maker

What is the prognosis for individuals with Kikuchi disease?

Kikuchi disease is generally an acute condition with a favorable prognosis. About 3 to 4% of patients experience recurrence. Lymphadenopathy usually resolves within 1-6 months after onset, although it may persist longer.[1][2]

Some patients go on to develop systemic lupus erythematous (SLE) years later.[1][2] SLE is a chronic autoimmune disorder that may affect the skin, joints, kidneys, and other organs. Symptoms vary from person to person. Almost all people with SLE have joint pain and swelling. Some develop arthritis. Frequently affected joints are the fingers, hands, wrists, and knees. Other common symptoms include chest pain when taking a deep breath, general discomfort or ill feeling, and mouth sores.[3]
Last updated: 4/6/2011

  1. Bosch X & Guilabert A. Kikuchi-Fujimoto disease. Orphanet. 2006; . Accessed 4/6/2011.
  2. Boone J, Kuzma CS. Kikuchi Disease. eMedicine. 2009; Accessed 4/6/2011.
  3. Borigini MJ. Systemic lupus erythematosus. MedlinePlus. February 2010; Accessed 4/6/2011.