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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Kikuchi disease


Other Names for this Disease

  • Histiocytic necrotising lymphadenitis
  • Kikuchi necrotizing lymphadenitis
  • Kikuchi's disease
  • Kikuchi-Fujimoto's disease
  • Nosocomial Kikuchi's disease
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Prognosis

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What is the long-term outlook for people with Kikuchi disease?

Kikuchi disease generally has a good prognosis. Lymphadenopathy usually goes away 1-6 months after onset, although it may last longer. About 3% to 4% of people have recurrence of the condition. [1][2]

Some people go on to develop systemic lupus erythematous (SLE) (lupus) years later.[1][2] SLE is a chronic autoimmune disorder that may affect the skin, joints, kidneys, and other organs. Symptoms vary from person to person. Almost all people with SLE have joint pain and swelling. Some develop arthritis. Joints commonly affected include those of the fingers, hands, wrists, and knees. Other symptoms may include chest pain when taking a deep breath; general discomfort or ill feeling; and/or mouth sores.[3]
Last updated: 10/15/2014

References
  1. Bosch X & Guilabert A. Kikuchi-Fujimoto disease. Orphanet. 2006; http://www.ojrd.com/content/1/1/18 . Accessed 4/6/2011.
  2. Boone J, Kuzma CS. Kikuchi Disease. eMedicine. 2009; http://emedicine.medscape.com/article/210752-overview. Accessed 4/6/2011.
  3. Borigini MJ. Systemic lupus erythematosus. MedlinePlus. February 2010; http://www.nlm.nih.gov/medlineplus/ency/article/000435.htm. Accessed 4/6/2011.


Other Names for this Disease
  • Histiocytic necrotising lymphadenitis
  • Kikuchi necrotizing lymphadenitis
  • Kikuchi's disease
  • Kikuchi-Fujimoto's disease
  • Nosocomial Kikuchi's disease
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.