Other Names for this Disease
- Angiolymphoid hyperplasia with eosinophilia
- Eosinophilic granuloma of soft tissue
- Eosinophilic hyperplastic lymphogranuloma
- Eosinophilic lymphofollicular granuloma
- Eosinophilic lymphofolliculosis
Your QuestionI have Kimura disease on my ear lobe. My right ear lobe has a swollen lump which was removed 4 years ago, but it returned one month later. Last year, I treated it with prednisone for 2 weeks which caused the lump to shrink back to normal. When the dosage of prednisone was halved, the lump started to come back again. I am currently taking the higher dose of prednisone once again. I want to know if there is any other medication for this disease.
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For individuals with symptoms caused by Kimura disease, surgery to remove the nodules is the treatment of choice; however, the nodules often reappear after surgery. 
Steroids (such as prednisone), taken by mouth or via an injection in the skin, can shrink the nodules but rarely result in a cure. Other, less common, treatments include oral pentoxifylline, medication that supresses the immune system (such as cyclosporine), radiotherapy, and a combination of all trans-retinoic acid and prednisone.  It is important to consult with your healthcare provider before taking any medication.
- Larroche C, Blétry O . Kimura's disease. Orphanet. February, 2005; http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=482. Accessed 1/19/2011.
- Wanat K, James A. Kimura Disease: Treatment & Medication. Emedicine. January 10, 2010; http://emedicine.medscape.com/article/1098777-treatment. Accessed 1/20/2011.