Lambert Eaton myasthenic syndrome
Other Names for this Disease
- Eaton Lambert syndrome
- Lambert Eaton syndrome
- Myasthenic syndrome of Lambert-Eaton
- Myasthenic-Myopathic syndrome of Lambert-Eaton
Your QuestionMy husband had Lambert Eaton myasthenic syndrome. Are our two children at risk to develop this condition?
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Questions on this page
While the condition is not known to follow a specific pattern of inheritance, there appears to be a genetic predisposition to autoimmune diseases in general. Families with a history of Lambert Eaton myasthenic syndrome may benefit from consulting with a genetics professional.
Genetics clinics are a source of information for individuals and families regarding genetic conditions, treatment, inheritance, and genetic risks to other family members. More information about genetic consultations is available from Genetics Home Reference. To find a genetics clinic, we recommend that you contact your primary healthcare provider for a referral.
The following online resources can help you find a genetics professional in your community:
- GeneTests has a searchable directory of US and international genetics and prenatal diagnosis clinics.
- The National Society of Genetic Counselors provides a searchable directory of US and international genetic counseling services.
- The American College of Medical Genetics has a searchable database of US genetics clinics.
- The American Society of Human Genetics maintains a database of its members, which includes individuals who live outside of the United States. Visit the link to obtain a list of the geneticists in your country, some of whom may be researchers that do not provide medical care.
- NINDS Lambert-Eaton Myasthenic Syndrome Information Page. Institute of Neurological Disorders and Stroke (NINDS). 2007; http://www.ninds.nih.gov/disorders/lambert_eaton/lambert_eaton.htm. Accessed 10/28/2009.
- Kleinschmidt P. Lambert-Eaton Myasthenic Syndrome. eMedicine. 2009; http://emedicine.medscape.com/article/792803-overview. Accessed 10/28/2009.
- Rugo HS. Chapter 189 - Paraneoplastic Syndromes and Other Non-Neoplastic Effects of Cancer. In: Goldman L, Ausiello D - editors. Cecil Medicine, 23rd edition. Philadelphia, PA: Saunders; 2007;
- Stickler DE, Sanders DB. Lambert-Eaton Myasthenic Syndrome. eMedicine. 2009; http://emedicine.medscape.com/article/1170810-overview. Accessed 10/28/2009.
- Lambert-Eaton Myasthenic Syndrome (LES). Muscular Dystrophy Association (MDA). 2009; http://www.mda.org/disease/lems.html. Accessed 10/28/2009.
- Friedman DI. Chapter 9.16 - Disorders of the Neuromuscular Junction. In: Yanoff M, Duker JS - editors. Ophthalmology, 3rd edition. United Kingdom: Mosby; 2008;