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Genetic and Rare Diseases Information Center (GARD)

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Langerhans cell histiocytosis

Other Names for this Disease
  • Eosinophilic granuloma (formerly)
  • Hand-Schüller-Christian syndrome (formerly)
  • Histiocytosis X
  • LCH
  • Letterer-Siwe disease (formerly)
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Your Question

My daughter was diagnosed with Langerhans cell histiocytosis. How is this condition treated?

Our Answer

We have identified the following information that we hope you find helpful. If you still have questions, please contact us.

What type of physician most commonly treats an individual with Langerhans cell histiocytosis (LCH)?

Most often an oncologist/hematologist takes the main role in treating patients with LCH. However, since LCH can affect so many areas of the body, sometimes a team approach may be appropriate, and the oncologist may enlist the help of various types of specialists, including radiologists, surgeons, pulmonologists, dermatologists, dentists, and others.
Last updated: 6/23/2008

How might Langerhans cell histiocytosis be treated?

Treatment for Langerhans cell histiocytosis (LCH) depends upon the individual patient; it may differ depending on the type and severity of the condition as well as what part(s) of the body are affected. In some cases, the disease will regress without any treatment at all. In other cases, limited surgery and small doses of radiation therapy or chemotherapy will be needed, depending on the extent of the disease. Treatment is planned after complete evaluation of the patient, with the goal of using as little treatment as possible to keep the disease under control.[1]

Detailed information about the treatment of LCH can be viewed on Medscape Reference's Web site.
Last updated: 12/2/2013