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Genetic and Rare Diseases Information Center (GARD)

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Langerhans cell histiocytosis

Other Names for this Disease
  • Eosinophilic granuloma (formerly)
  • Hand-Schüller-Christian syndrome (formerly)
  • Histiocytosis X
  • LCH
  • Letterer-Siwe disease (formerly)
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How might Langerhans cell histiocytosis be treated?

Treatment for Langerhans cell histiocytosis (LCH) depends upon the individual patient; it may differ depending on the type and severity of the condition as well as what part(s) of the body are affected. In some cases, the disease will regress without any treatment at all. In other cases, limited surgery and small doses of radiation therapy or chemotherapy will be needed, depending on the extent of the disease. Treatment is planned after complete evaluation of the patient, with the goal of using as little treatment as possible to keep the disease under control.[1]

Detailed information about the treatment of LCH can be viewed on Medscape Reference's Web site.
Last updated: 12/2/2013

  1. LCH in Children. Histiocytosis Association of America. Accessed 5/7/2012.

Clinical Trials & Research for this Disease

  • lists trials that are studying or have studied Langerhans cell histiocytosis. Click on the link to go to to read descriptions of these studies.