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Genetic and Rare Diseases Information Center (GARD)

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Lemierre syndrome


Other Names for this Disease

  • Necrobacillosis
  • Oropharyngeal infection leading to secondary septic thrombophlebitis of the internal jugular vein
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Overview

Lemierre syndrome is a rare disease that is typically characterized by the following four findings: (1) pharyngitis or tonsillitis; followed by (2) oropharyngeal infection with Fusobacterium necrophorum, a bacteria that is normally present in the pharynx, gastrointestinal tract, and genital tract of humans; leading to (3) internal jugular vein thrombosis; and subsequent (4) septic emboli (pus-containing tissue that migrates from its original location in the body to the lungs or other parts of the body). Antibiotics are usually the primary treatment.[1]
Last updated: 11/12/2008

References

  1. Schwartz RH. Chapter 30: Infections Related to the Upper and Middle Airways. In: Long SS, Pickering LK, Prober CG. Long: Principles and Practice of Pediatric Infectious Diseases, 3rd ed. PA: Churchill Livingstone, An Imprint of Elsevier; 2008;
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In Depth Information

  • Orphanet is a European reference portal for¬†information on rare diseases and orphan drugs.¬† Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Lemierre syndrome. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • Necrobacillosis
  • Oropharyngeal infection leading to secondary septic thrombophlebitis of the internal jugular vein
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.