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Genetic and Rare Diseases Information Center (GARD)

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Loin pain hematuria syndrome

Other Names for this Disease
  • LPHS
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How might loin pain-hematuria syndrome be treated?

Treatment of loin pain-hematuria syndrome (LPHS) typically consists of pain management. Narcotics or oral opioids may be prescribed to help control pain. Patients with severe pain may need high-dose opioids daily or almost daily. Occasionally, people with LPHS require hospitalization for intravenous opioid therapy and control of nausea.[1]

Other treatments may include denervation, autotransplantation, renal neurectomy, or nephrectomy. Unfortunately symptoms often recur following these procedures. Limited evidence suggests that drugs that inhibit angiotensin may reduce the frequency and severity of episodes of loin pain and gross hematuria.[1]

Last updated: 10/7/2013

  1. Hebert, LA. Loin pain-hematuria syndrome. In: Forman, JP (Ed). UpToDate. Waltham, MA: UpToDate; 2012;