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Genetic and Rare Diseases Information Center (GARD)

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Loin pain hematuria syndrome

Other Names for this Disease
  • LPHS
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What are the signs and symptoms of loin pain-hematuria syndrome?

Most people with loin pain-hematuria syndrome (LPHS) have both loin pain and hematuria, but some have only one of these symptoms. The loin pain is sometimes described as burning or throbbing. The pain may be present in one or both sides of the body, and it can be made worse by movement or exercise. Pain episodes may last from hours to months and can be accompanied by painful urination, low-grade fever, and/or nausea. People with LPHS may experience gross hematuria (visible blood in the urine). This is almost always associated with worsening pain. Up to half of people with LPHS also have kidney stones.[1]
Last updated: 10/7/2013

  1. Hebert, LA. Loin pain-hematuria syndrome. In: Forman, JP (Ed). UpToDate. Waltham, MA: UpToDate; 2012;