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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Malignant mixed Mullerian tumor


Other Names for this Disease
  • Carcinosarcoma
  • Mixed Mullerian tumor
  • Mixed tumor, Mullerian
  • MMMT
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Your Question

My mom passed away with MMT Uterine Cancer. The doctors tell me its very rare. I'm still unsure and wanted to know more about this cancer and if it is genetic.

Our Answer

We have identified the following information that we hope you find helpful. If you still have questions, please contact us.

Is there a genetic cause of malignant mixed Mullerian tumor of the uterus?

Presently, there are no known hereditary causes of mixed Mullerian tumor. Researchers have identified some risk factors for the development of this type of tumor. These risk factors include: nulliparity, older age ( > 50 years old), obesity, exposure to estrogen and long term use of tamoxifen. Oral contraceptive use has been found to help lower the risk of developing a malignant mixed Mullerian tumor.[1]
Last updated: 12/10/2012

References
  • Kanthan, Senger. Uterine Carcinosarcomas (Malignant Mixed Müllerian Tumours): A Review with Special Emphasis on the Controversies in Management. Obstetrics and Gynecology International. 2011; 10:1155. http://www.hindawi.com/journals/ogi/2011/470795/. Accessed 12/10/2012.