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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Mantle cell lymphoma


Other Names for this Disease
  • Lymphoma, mantle cell
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Treatment


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How might Mantle cell lympoma be treated?

Various treatmentsare currently available for Mantle cell lymphomas. Rare cases of early stage mantle cell lymphomas may be treated with radiation therapy. [1] For more advance stagestreatment includes chemotherapy, immunotherapy, bone marrow transplant, and medication. [1]
Last updated: 7/21/2011

References
  1. Non Hodgkin Lymphoma. American Cancer Society. October 2010; http://www.cancer.org/acs/groups/cid/documents/webcontent/003126-pdf.pdf. Accessed 7/11/2011.
  2. O’Connor OA and Vose JM. Mantle Cell Lymphoma: Getting the Facts. Lymphoma Research Foundation.. http://www.lymphoma.org/atf/cf/%7B0363CDD6-51B5-427B-BE48-E6AF871ACEC9%7D/MANTLE%20CELL.PDF. Accessed 7/11/2011.


Clinical Trials & Research for this Disease

  • ClinicalTrials.gov lists trials that are studying or have studied Mantle cell lymphoma. Click on the link to go to ClinicalTrials.gov to read descriptions of these studies.

Medical Products

The medication(s) listed in the table(s) below have been approved by the Food and Drug Administration (FDA) for treatment of this condition. The FDA Office of Orphan Products Development designates "orphan products" for those that treat rare diseases affecting fewer than 200,000 Americans. The table(s) below may not be an exhaustive list of drugs or products used to treat this condition. There may be other products available that are not considered orphan products. To search for all FDA approved drugs, visit Drugs@FDA. You can find orphan products used to treat other conditions by searching the Orphan Drug Product Designation database.


Generic Name ibrutinib
Trade Name
(Manufacturer Name)
Imbruvica
(Pharmacyclics, Inc.)
Indication
The FDA has approved this product to be used in this manner.
Treatment of patients with mantle cell lymphoma (MCL) who have received at least one prior therapy. Treatment of patients with chronic lymphocytic leukemia (CLL) who have received at least one prior therapy.
More Information about this product Drug Information Portal

Generic Name Lenolidomide
Trade Name
(Manufacturer Name)
Revlimid
Indication
The FDA has approved this product to be used in this manner.
Treatment of mantle cell lymphoma whose disease has relapsed or progressed after two prior therapies, one of which included bortezomib.
More Information about this product Drug Information Portal