Your browser does not support javascript:   Search for gard hereSearch for news-and-events here.

Diseases

Genetic and Rare Diseases Information Center (GARD)

Print friendly version

Marchiafava Bignami disease


Other Names for this Disease
  • Acute Marchiafava-Bignami disease
  • Chronic Marchiafava-Bignami syndrome
  • MBD
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Cause


Newline Maker

What causes Marchiafava Bignami disease?

The exact cause of Marchiafava Bignami disease is not known. Alcoholism seems to be the greatest risk factor for the disease, although rare cases have occurred in individuals who did not drink alcohol. Nutritional factors have been suspected, but no specific nutrient has been identified.[1] Other possible causes include electrolyte disturbances or direct toxicity of ethanol or other substances.[2][1]
Last updated: 6/1/2011

References
  1. Jennifer Ault. Marchiafava-Bignami Disease. eMedicine. February 3, 2010; http://emedicine.medscape.com/article/1146086-overview#showall. Accessed 5/31/2011.
  2. Walter G. Bradley et al. Neurology in Clinical Practice, 5th ed.. USA: Butterworth-Heinemann; 2008 ;