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Marcus Gunn phenomenon
Other Names for this Disease
- Familial Marcus Gunn phenomenon (subtype)
- Marcus Gunn syndrome
- Maxillopalpebral synkinesis
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Marcus Gunn phenomenon is a rare condition characterized by movement of the upper eyelid in a rapid rising motion (a "wink") each time the jaw moves. The wink phenomenon may be elicited by opening the mouth, thrusting the jaw to the side, jaw protrusion, chewing, smiling, or sucking. It is usually present at birth and may occur with other eye abnormalities (such as strabismus) or vision problems.[ Although it is usually unilateral, it can affect both eyes in rare cases. The exact cause is not known. Marcus Gunn phenomenon is generally sporadic, but familial cases with autosomal dominant inheritance have been reported. Treatment is not always needed but may include surgery in more severe cases.
- Marcus Gunn Phenomenon. National Organization for Rare Disorders (NORD). http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=Marcus%20Gunn%20Phenomenon. Accessed July 1, 2009.
- Sean M Blaydon. Marcus Gunn Jaw-winking Syndrome. Medscape Reference. http://emedicine.medscape.com/article/1213228-overview. Accessed March 5, 2013.
- Marcus-Gunn syndrome. Orphanet. http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=91412. Accessed March 4, 2013.
- Marcus Gunn Phenomenon. Marcus Gunn Phenomenon. http://www.rarediseases.org/rare-disease-information/rare-diseases/byID/833/viewAbstract. Accessed March 6, 2013.
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- Medscape Reference provides information on this topic. Click on the link to view this information. You may need to register to view the medical textbook, but registration is free.
- The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders. Click on the link to view information on this topic.
- Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge. Click on the link to read information on this topic.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Marcus Gunn phenomenon. Click on the link to view a sample search on this topic.
- The The Online Mendelian Inheritance in Man (OMIM) database contains genetics resources that discuss Marcus Gunn phenomenon. Click on the link to go to OMIM and review these resources.