- Mast cell disease
Your QuestionIs mastocytosis contagious?
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In some cases, mastocytosis is inherited. These cases result from a genetic mutation which causes the over-activation of the receptor for mast cell growth factor (c-kit). This mutation is believed to cause the abnormal accumulation of mast cells in certain tissues. These mutations in the c-kit proto-oncogene are passed down through families in an autosomal dominant fashion.
- FAQ. Mastocytosis Society Canada. 2013; http://www.mastocytosis.ca/mastofaq.htm. Accessed 5/15/2013.
- Mastocytosis. National Institute of Allergy and Infectious Diseases. January 2011; http://www.niaid.nih.gov/topics/mastocytosis/Pages/Default.aspx. Accessed 5/15/2013.
- Mastocytosis. National Organiation for Rare Disorders (NORD). 2007; http://www.rarediseases.org/rare-disease-information/rare-diseases/byID/441/viewAbstract. Accessed 5/15/2013.
- Mast Cell Disease. Online Mendelian Inheritance in Man (OMIM). 2012; http://omim.org/entry/154800. Accessed 5/15/2012.