McCune Albright syndrome
Other Names for this Disease
- Albright syndrome
- Albright's disease
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.
On this page
McCune Albright syndrome (MAS) is not inherited. It is caused by a random change (mutation) in the GNAS gene that occurs very early in development. As a result, some of the body's cells have a normal version of the GNAS gene, while other cells have the mutated version. This phenomenon is called mosaicism. The severity of this disorder and its specific features depend on the number and location of cells that have the mutated GNAS gene. This mutation is not passed on to any of the affected individual's children.
Last updated: 12/26/2013
- McCune-Albright syndrome. Genetics Home Reference (GHR). January 2009; http://ghr.nlm.nih.gov/condition=mccunealbrightsyndrome. Accessed 10/17/2013.
- Haldeman-Englert C. McCune-Albright syndrome. MedlinePlus. 2012; http://www.nlm.nih.gov/medlineplus/ency/article/001217.htm. Accessed 10/17/2013.