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McCune Albright syndrome
Other Names for this Disease
- Albright syndrome
- Albright's disease
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McCune-Albright syndrome is a disease that affects the bones, skin, and several hormone-producing (endocrine) tissues. This multisystem disorder is characterized by: replacement of normal bone tissue with areas of abnormal fibrous growth (fibrous dysplasia); patches of abnormal skin pigmentation (i.e., areas of light-brown skin [cafe-au-lait spots] with jagged borders); and abnormalities in the glands that regulate the body’s rate of growth, its sexual development, and certain other metabolic functions (multiple endocrine dysfunction). This condition results from a change (or mutation) in a gene that occurs by chance in the womb. Because it occurs by chance, it is not inherited and passed down from one generation to the next.
- McCune-Albright syndrome. Genetics Home Reference (GHR). http://ghr.nlm.nih.gov/condition=mccunealbrightsyndrome. Accessed March 8, 2011.
- Chambers D. McCune-Albright syndrome. MedlinePlus. http://www.nlm.nih.gov/medlineplus/ency/article/001217.htm. Accessed March 8, 2011.
- McCune-Albright Syndrome. National Institute of Child Health and Human Development (NICHD). http://www.nichd.nih.gov/health/topics/mccune_albright_syndrome.cfm. Accessed July 20, 2009.
- McCune Albright Syndrome. National Organization for Rare Disorders (NORD). http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=McCune%20Albright%20Syndrome. Accessed July 20, 2009.
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- The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) provides information related to the health of children, adults, and families. Click on the link to view information on this topic.
- Genetics Home Reference (GHR) contains information on McCune Albright syndrome. Click on the link to go to GHR and review the information.
- MedlinePlus, a Web site designed by the National Library of Medicine to help you research your health questions, provides more information about this topic. Click on the link to view this information.
- Medscape Reference provides information on this topic. Click on the link to view this information. You may need to register to view the medical textbook, but registration is free.
- MeSH® (Medical Subject Headings) is a terminology tool used by the National Library of Medicine. Click on the link to view information on this topic.
- The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders. Click on the link to view information on this topic.
- Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge. Click on the link to read information on this topic.
- PubMed is a searchable database of medical literature and lists journal articles that discuss McCune Albright syndrome. Click on the link to view a sample search on this topic.
- The The Online Mendelian Inheritance in Man (OMIM) database contains genetics resources that discuss McCune Albright syndrome. Click on the link to go to OMIM and review these resources.