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Genetic and Rare Diseases Information Center (GARD)

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Meige syndrome


Other Names for this Disease
  • Blepharospasm-oromandibular dystonia
  • Brueghel syndrome
  • Idiopathic blepharospasm-oromandibular dystonia syndrome
  • Meige dystonia
  • Meige's syndrome
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Overview

Meige syndrome is a rare, neurological condition characterized by blepharospasm (abnormal movement of the eyelids); oromandibular dystonia (spasms in the jaw and tongue); and sometimes, cervical dystonia. Symptoms and severity can vary.[1][2] The exact cause of Meige syndrome is unknown, but researchers suspect that it is due to a combination of genetic and environmental factors. Treatment focuses on each person's symptoms and may include drug therapy and/or botulinum A toxin (Botox) injections.[1] Other treatment options, such as deep brain stimulation, are currently being considered.
Last updated: 2/17/2015

References

  1. Meige syndrome. NORD. April 14, 2008; http://www.rarediseases.org/rare-disease-information/rare-diseases/byID/235/viewAbstract.
  2. Lyons MK, Birch BD, Hillman RA, Boucher OK, Evidente VG. Long-term follow-up of deep brain stimulation for Meige syndrome. Neurosurg Focus. August, 2010; 29(2):
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Basic Information

In Depth Information

  • Orphanet is a European reference portal for information on rare diseases and orphan drugs.  Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Meige syndrome. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • Blepharospasm-oromandibular dystonia
  • Brueghel syndrome
  • Idiopathic blepharospasm-oromandibular dystonia syndrome
  • Meige dystonia
  • Meige's syndrome
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.