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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Mixed connective tissue disease


Other Names for this Disease
  • MCTD
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Cause

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What causes mixed connective tissue disease?

The exact underlying cause of mixed connective tissue disease (MCTD) is currently unknown. It is an autoimmune disorder, which means the immune system mistakes normal, healthy cells for those that that body should "fight off." There are ongoing studies exploring how immune system dysfunction may be involved in the development of this condition.[1][2]
Last updated: 12/29/2014

References
  1. Eric L Greidinger, MD. Mixed Connective-Tissue Disease. Medscape Reference. February 2013; http://emedicine.medscape.com/article/335815-overview.
  2. Mixed Connective Tissue Disease (MCTD). NORD. October 2007; http://www.rarediseases.org/rare-disease-information/rare-diseases/byID/338/viewAbstract.


Other Names for this Disease
  • MCTD
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.