Localized scleroderma
Overview
Localized scleroderma is characterized by thickening of the skin from excessive collagen deposits. Collagen is a protein normally present in our skin that provides structural support. However, when too much collagen is made, the skin becomes stiff and hard.[1] Localized types of scleroderma are those limited to the skin and related tissues and, in some cases, the muscle below. Internal organs are not affected by localized scleroderma, and localized scleroderma can never progress to the systemic form of the disease. Often, localized conditions improve or go away on their own over time, but the skin changes and damage that occur when the disease is active can be permanent. For some people, localized scleroderma is serious and disabling.[2]
There are two generally recognized types of localized scleroderma: morphea and linear.[2]
References
- Localized Scleroderma. Scleroderma Foundation. http://www.scleroderma.org/pdf/Medical_Brochures/Localized.pdf. Accessed June 23, 2011.
- . Scleroderma. National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS). http://www.niams.nih.gov/Health_Info/Scleroderma/. Accessed June 23, 2011.
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Selected Full-Text Journal Articles
- Select volumes of the Scleroderma Care and Research Jounal can be viewed by visiting the Scleroderma Clinical Trials Consortium Web site. Click on the link above to learn more.