Your browser does not support javascript:   Search for gard hereSearch for news-and-events here.

Diseases

Genetic and Rare Diseases Information Center (GARD)

Print friendly version

Localized scleroderma


Other Names for this Disease

  • Scleroderma, localized
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Overview

Localized scleroderma is characterized by thickening of the skin from excessive collagen deposits. Collagen is a protein normally present in our skin that provides structural support. However, when too much collagen is made, the skin becomes stiff and hard.[1] Localized types of scleroderma are those limited to the skin and related tissues and, in some cases, the muscle below. Internal organs are not affected by localized scleroderma, and localized scleroderma can never progress to the systemic form of the disease. Often, localized conditions improve or go away on their own over time, but the skin changes and damage that occur when the disease is active can be permanent. For some people, localized scleroderma is serious and disabling.[2]

There are two generally recognized types of localized scleroderma: morphea and linear.[2]

 

Last updated: 4/3/2012

References

  1. Localized Scleroderma. Scleroderma Foundation. http://www.scleroderma.org/site/DocServer/Localized.pdf?docID=317. Accessed 6/23/2011.
  2. . Scleroderma. National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS). May 2010; http://www.niams.nih.gov/Health_Info/Scleroderma/. Accessed 6/23/2011.
Your Questions Answered
by the Genetic and Rare Diseases Information Center

1 question(s) from the public on Localized scleroderma have been answered. See questions and answers. You can also submit a new question.

Basic Information

  • MedlinePlus was designed by the National Library of Medicine to help you research your health questions, and it provides more information about this topic.
  • The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) support research into the causes, treatment, and prevention of arthritis and musculoskeletal and skin diseases, the training of basic and clinical scientists to carry out this research, and the dissemination of information on research progress in these diseases. Click on the link to view information on this topic.

In Depth Information

  • Medscape Reference provides information on this topic. Click on the link to view this information. You may need to register to view the medical textbook, but registration is free.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Localized scleroderma. Click on the link to view a sample search on this topic.

Selected Full-Text Journal Articles

Other Names for this Disease
  • Scleroderma, localized
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.