Your browser does not support javascript:   Search for gard hereSearch for news-and-events here.

Diseases

Genetic and Rare Diseases Information Center (GARD)

Print friendly version

Multiple system atrophy


Other Names for this Disease
  • MSA
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Overview


Multiple system atrophy (MSA) is a progressive neurodegenerative disorder characterized by symptoms of autonomic nervous system failure such as fainting spells and bladder control problems, combined with motor control symptoms such as tremor, rigidity, and loss of muscle coordination.  MSA affects both men and women primarily in their 50s.  The disease tends to advance rapidly over the course of 9 to 10 years, with progressive loss of motor skills, eventual confinement to bed, and death.[1] The cause of multiple system atrophy is unknown, although environmental toxins, trauma, and genetic factors have been suggested.[2] There is no cure for this condition, and there is no known way to prevent the disease from getting worse. The goal of treatment is to control symptoms.[1][3] 
Last updated: 10/7/2010

References

  1. Multiple System Atrophy Fact Sheet. National Institute of Neurological Disorders and Stroke (NINDS). 2009; http://www.ninds.nih.gov/disorders/msa/detail_msa.htm. Accessed 10/7/2010.
  2. Diedrich A, Robertson D. Multiple System Atrophy. eMedicine. 2010; http://emedicine.medscape.com/article/1154583-overview. Accessed 10/7/2010.
  3. Multiple system atrophy. MedlinePlus. 2008; http://www.nlm.nih.gov/medlineplus/ency/article/000757.htm. Accessed 10/7/2010.
Your Questions Answered
by the Genetic and Rare Diseases Information Center

Please contact us with your questions about Multiple system atrophy. We will answer your question and update these pages with new resources and information.

Basic Information

In Depth Information

  • Medscape Reference provides information on this topic. Click on the link to view this information. You may need to register to view the medical textbook, but registration is free.
  • The Online Mendelian Inheritance in Man (OMIM) is an catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine. 
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs.  Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Multiple system atrophy. Click on the link to view a sample search on this topic.

Insurance Issues