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Genetic and Rare Diseases Information Center (GARD)

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Multiple myeloma

Other Names for this Disease
  • Kahler disease
  • Myeloma - multiple
  • Myelomatosis
  • Plasma cell dyscrasia
  • Plasma cell myeloma
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What are the signs and symptoms of multiple myeloma?

Multiple myeloma causes anemia, which makes a person more likely to get infections and have abnormal bleeding. As the cancer cells grow in the bone marrow, bone or back pain can occur, most often in the ribs or back. If the bones in the spine are affected, it can put pressure on the nerves, resulting in numbness or weakness of the arms or legs. Other symptoms include:[1][2]

  • Bleeding problems
  • Fatigue and weakness due to anemia
  • Frequent infections and fevers without any other cause
  • Shortness of breath due to anemia
  • Unexplained broken bones
  • Weight loss
  • Nausea or constipation
Last updated: 7/6/2011

  1. What You Need To Know About Multiple Myeloma. National Cancer Institute. November 20, 2008; Accessed 7/6/2011.
  2. Multiple Myeloma. MedlinePlus. February 2011; Accessed 7/6/2011.