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Genetic and Rare Diseases Information Center (GARD)

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Mycobacterium Avium Complex


Other Names for this Disease

  • MAC
  • MAI
  • Mycobacterium Avium
  • Mycobacterium Avium-Intracellulare
  • Mycobacterium Avium-Intracellulare infection
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Overview

Mycobacterium avium complex (MAC) refers to infections caused by two types of bacteria, Mycobacterium avium and Mycobacterium intracellulare.[1] Is is associated with several different conditions including pulmonary MAC, which affects the lungs; disseminated MAC, which affects many different parts of the body; and MAC lymphadenitis, which causes swollen lymph nodes. MAC is spread when the bacteria, which can be found in water, soil and dust particles, are inhaled or ingested. Although these infections can occur in anyone, MAC primarily affects people who are immune compromised (i.e. - due to AIDS, lymphoma) or have underlying lung disease (i.e. COPD, lung cancer, cystic fibrosis).[2] Treatment for MAC varies depending on the type of condition but may include antibiotics, antituberculosis drugs and/or surgery.[1][2]   
Last updated: 12/13/2014

References

  1. Judith S Currier, MD. Mycobacterium avium complex (MAC) infections in HIV-infected patients. UpToDate. May 2014;
  2. Janak Koirala, MD, MPH, FACP, FIDSA. Mycobacterium Avium-Intracellulare. Medscape Reference. March 2014; http://emedicine.medscape.com/article/222664-overview.
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Basic Information

  • You can obtain information on this topic from the Centers for Disease Control and Prevention (CDC). The CDC is recognized as the lead federal agency for developing and applying disease prevention and control, environmental health, and health promotion and education activities designed to improve the health of the people of the United States.

In Depth Information

  • Medscape Reference provides information on this topic. Click on the link to view this information. You may need to register to view the medical textbook, but registration is free.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Mycobacterium Avium Complex. Click on the link to view a sample search on this topic.
  • The AIDS Education and Training Center (AETC)¬†offers information¬†on Mycobacterium Avium Complex. Click on the link to view this information page.
Other Names for this Disease
  • MAC
  • MAI
  • Mycobacterium Avium
  • Mycobacterium Avium-Intracellulare
  • Mycobacterium Avium-Intracellulare infection
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.