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Inflammatory myofibroblastic tumor

Other Names for this Disease
  • Inflammatory fibrosarcoma
  • Inflammatory pseudotumor
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Inflammatory myofibroblastic tumor is made up of specific cells called myofibroblastic spindle cells. This tumor can occur in many different parts of the body, but it occurs most frequently in the lungs, soft tisues, or internal organs. Inflammatory myofibroblastic tumor usually develops in children or young adults, although it can affect people of any age. This type of tumor tends to recur in the same location, but it rarely spreads (metastasizes) to other parts of the body. Approximately 50% of inflammatory myofibroblastic tumors have rearrangements of the ALK gene on chromosome 2. Treatment typically involves surgery to remove the tumor.
Last updated: 11/2/2010


  1. Coffin CM, Hornick JL, Fletcher CD. American Journal of Surgical Pathology. April 2007; 31(4):509-520. Accessed 11/2/2010.
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