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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Glycine encephalopathy


Other Names for this Disease

  • Glycine synthase deficiency
  • Hyperglycinemia nonketotic
  • Nonketotic hyperglycinemia
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Inheritance

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How is glycine encephalopathy inherited?

Glycine encephalopathy is inherited in an autosomal recessive pattern, which means in an affected individual, both copies of the gene that cause this condition have mutations. The parents of an individual with an autosomal recessive condition each carry one copy of the mutated gene and are referred to as carriers. Carriers typically do not show signs and symptoms of the condition.[1] When two carriers of an autosomal recessive condition have children, each child has a 25% (1 in 4) risk to have the condition, a 50% (1 in 2) risk to be a carrier like each of the parents, and a 25% chance to not have the condition and not be a carrier.
Last updated: 10/28/2011

References
  1. Glycine encephalopathy. Genetics Home Reference Website. April 2007; http://ghr.nlm.nih.gov/condition=glycineencephalopathy. Accessed 10/7/2008.


Other Names for this Disease
  • Glycine synthase deficiency
  • Hyperglycinemia nonketotic
  • Nonketotic hyperglycinemia
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.