Other Names for this Disease
- Congenital hereditary lymphedema
- Early onset lymphedema
- Hereditary lymphedema
- Hereditary lymphedema 1
- Milroy's disease
Your QuestionI have two older brothers with Milroy disease. I do not exhibit any signs or symptoms of the condition. I am currently pregnant and was under the impression that since I do not show the signs of Milroy disease that my offspring would not be at risk for this disorder. Am I correct in my understanding that an autosomal dominant trait must be present in order to be passed on to offspring?
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Questions on this page
Estimating the chance of developing or passing on a genetic disorder can be complex. Genetics professionals can help people understand these chances and help them make informed decisions about their health.
You can learn more about the difference between clinical and research testing at the following information page developed by the Genetic Home Reference.
Genetics clinics are a source of information for individuals and families regarding genetic conditions, treatment, inheritance, and genetic risks to other family members. More information about genetic consultations is available from Genetics Home Reference. To find a genetics clinic, we recommend that you contact your primary healthcare provider for a referral.
The following online resources can help you find a genetics professional in your community:
- The National Society for Genetic Counselors provides a searchable directory of US and international genetic counseling services.
- The American College of Medical Genetics has a searchable database of US genetics clinics.
- The University of Kansas Medical Center provides a list of US and international genetic centers, clinics, and departments.
- The American Society of Human Genetics maintains a database of its members, which includes individuals who live outside of the United States. Visit the link to obtain a list of the geneticists in your country, some of whom may be researchers that do not provide medical care.
- What are reduced penetrance and variable expressivity?. Genetics Home Reference. 2011; http://ghr.nlm.nih.gov/handbook/inheritance/penetranceexpressivity. Accessed 7/29/2011.
- Milroy disease. Genetic Home Reference. 2008; http://ghr.nlm.nih.gov/condition=milroydisease. Accessed 7/29/2011.
- Brice GW, Mansour S, Ostergaard P, Connell F, Jeffery S, Mortimer P. Milroy Disease. GeneReviews. 2009; http://www.ncbi.nlm.nih.gov/books/NBK1239/. Accessed 7/29/2011.