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Genetic and Rare Diseases Information Center (GARD)

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Other Names for this Disease
  • Idiopathic hypertrophic osteoarthropathy
  • PDP
  • Primary hypertrophic osteoarthropathy
  • Touraine Solente Gole syndrome
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How might pachydermoperiostosis be treated?

Treatment for pachydermoperiostosis mainly focuses on the specific signs and symptoms present in each individual.[1] Bone and joint pain may be treated with nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids or colchicine.[1][2] A vagotomy, a surgical procedure in which certain branches of the vagus nerve are cut, may in some instances improve joint pain and swelling.[1] Skin-related symptoms may be treated with retinoids.[2] Plastic surgery may be performed to improve facial appearance in some individuals.[1] Surgery may also be performed to treat clubbing of fingers and/or toes.[2]
Last updated: 5/9/2012

  1. Pachydermoperiostosis. NORD. November 17, 2008; Accessed 5/9/2012.
  2. Hermann Girschick. Pachydermoperiostosis. Orphanet. January 2011; Accessed 5/9/2012.

Clinical Trials & Research for this Disease

  • The U.S. National Institutes of Health, through the National Library of Medicine, developed to provide patients, family members, and members of the public with current information on clinical research studies. There is a study titled Evaluation and Treatment of Skeletal Diseases which may be of interest to you.